{"id":11878,"date":"2025-08-19T12:32:37","date_gmt":"2025-08-19T12:32:37","guid":{"rendered":"https:\/\/vw-ingredients.com\/m\/s-boulardii-ureticisi"},"modified":"2025-10-27T09:34:11","modified_gmt":"2025-10-27T09:34:11","slug":"s-boulardii-ureticisi","status":"publish","type":"manufacturer","link":"https:\/\/vw-ingredients.com\/tr\/m\/s-boulardii-ureticisi","title":{"rendered":"S. Boulardii \u00dcreticisi"},"content":{"rendered":"\t\t
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Saccharomyces boulardii nedir?<\/h2>

Saccharomyces boulardii, ilk olarak 1934 y\u0131l\u0131nda Henri Boulard ad\u0131nda bir Frans\u0131z bilim adam\u0131 taraf\u0131ndan \u00c7inhindi’ndeki li\u00e7i ve mangosten meyvelerinden izole edilen tropikal bir maya t\u00fcr\u00fcd\u00fcr. Saccharomyces boulardii, Saccharomyces cerevisiae’ye benzemekle birlikte patojenik olmayan ve biyoterap\u00f6tik \u00f6zellikleri bak\u0131m\u0131ndan farkl\u0131l\u0131k g\u00f6sterir. \u00c7ok \u00e7e\u015fitli gastrointestinal bozukluklarla m\u00fccadele eden etkili bir probiyotik oldu\u011fu bulunmu\u015ftur ve d\u00fcnya \u00e7ap\u0131nda 90 \u00fclkede ticari olarak mevcuttur. S. boulardii’nin sistemik olmad\u0131\u011f\u0131, sadece gastrointestinal sistemde d\u00fc\u015f\u00fck pH seviyelerinde hayatta kald\u0131\u011f\u0131 ve 37\u00b0C’ye kadar s\u0131cakl\u0131klarda \u00fcreyebildi\u011fi tespit edilmi\u015ftir (3). S. boulardii, \u00f6zellikle di\u011fer mikroplarla olan \u00e7ok \u00e7e\u015fitli etkile\u015fimleri ve gastrointestinal bozukluk ve ishal semptomlar\u0131n\u0131 devre d\u0131\u015f\u0131 b\u0131rakma yetene\u011fi nedeniyle d\u00fcnya \u00e7ap\u0131nda ilgi uyand\u0131rm\u0131\u015ft\u0131r. Mevcut ara\u015ft\u0131rmalar taksonomi bilimini, \u00f6zellikle de S. boulardii ve yak\u0131n akrabas\u0131 S. cerevisiae aras\u0131ndaki ili\u015fkiyi incelemektedir. Genomik yap\u0131s\u0131 neredeyse %100 benzer olmas\u0131na ve \u00e7o\u011fu ki\u015finin ayn\u0131 t\u00fcrden olmalar\u0131 gerekti\u011fini savunmas\u0131na ra\u011fmen, S. boulardii en zorlu ko\u015fullarda hayatta kalmas\u0131n\u0131 sa\u011flayan benzersiz yeteneklere sahiptir. <\/p>

Saccharomyces Boulardii’nin Faydalar\u0131<\/h2>
  • Saccharomyces boulardii, \u00e7e\u015fitli gastrointestinal bozukluklar\u0131n, anti-biyotik ili\u015fkili ishalin, nazogastrik t\u00fcp ili\u015fkili ishalin, hem \u00e7ocuklarda hem de yeti\u015fkinlerde ishalin ve viral enfeksiyon ili\u015fkili ishalin tedavisinde kullan\u0131l\u0131r. Ayr\u0131ca mikrobik hastal\u0131klara neden olan toksinlerin etkilerini zay\u0131flatt\u0131\u011f\u0131 da g\u00f6sterilmi\u015ftir. <\/li>
  • S. boulardii’nin ayr\u0131ca pro-enflamatuar sitokinler \u00fczerinde inhibe edici yetenekleri olan \u00e7e\u015fitli proteazlar salg\u0131lad\u0131\u011f\u0131 bilinmektedir.<\/li>
  • S. boulardii’nin insan v\u00fccudunun gastrointestinal sistemindeki \u00e7e\u015fitli mikroplarla etkile\u015fime girdi\u011fi ve inflamasyona neden olan ajanlar \u00fczerinde inhibit\u00f6r etkiler g\u00f6sterdi\u011fi bulunmu\u015ftur. S. boulardii’nin ishale neden olan ajanlar\u0131n ve bunlarla ili\u015fkili toksinlerin konsantrasyonunu azaltt\u0131\u011f\u0131 g\u00f6sterilmi\u015ftir. Yeti\u015fkinlerde, \u00e7ocuklarda ve bebeklerde akut ishal, AIDS hastalar\u0131nda kronik ishal (21) ve bakteriyel enfeksiyonlar\u0131n neden oldu\u011fu ishal dahil olmak \u00fczere t\u00fcm ishal t\u00fcrleri S. boulardii taraf\u0131ndan etkili bir \u015fekilde giderilmektedir.<\/li>
  • S. boulardii, \u00f6zellikle Clostridium difficile’den muzdarip hastalarda anti-biyotik ili\u015fkili ishale kar\u015f\u0131 bir sava\u015f\u00e7\u0131 olarak kullan\u0131lm\u0131\u015ft\u0131r.C. difficile enfeksiyonu, ba\u011f\u0131rsak astar\u0131ndaki do\u011fal mikrofloray\u0131 ortadan kald\u0131ran, kolonda iltihaplanmaya ve ishale neden olan anti-biyotik tedavilerden kaynaklan\u0131r. S. boulardii’nin sindirim sistemindeki bir dizi mikrofloray\u0131 yeniledi\u011fi bulunmu\u015ftur. C. difficile, yeti\u015fkinlerde nozokomiyal ishalden sorumlu iki toksin (A & B) \u00fcreten bir anaerobdur. \u00c7al\u0131\u015fmalar, S. boulardii’nin C. difficile seviyelerini d\u00fc\u015f\u00fcrd\u00fc\u011f\u00fcn\u00fc, ancak en belirgin etkinin C. difficile taraf\u0131ndan \u00fcretilen A ve B toksinlerinin konsantrasyonundaki azalma oldu\u011funu ortaya koymu\u015ftur. S. boulardii bunu, toksin A ve B’yi ve bunlar\u0131n f\u0131r\u00e7a s\u0131n\u0131r\u0131 membran resept\u00f6rlerini proteolitik olarak sindiren 54-kDa proteaz\u0131 serbest b\u0131rakarak yapar. Buna ek olarak, S. boulardii C. difficile b\u00fcy\u00fcmesini inhibe eder ve ba\u011f\u0131rsak mukozal ba\u011f\u0131\u015f\u0131kl\u0131k tepkisini artt\u0131rmak i\u00e7in konak mukozal aktivitesini uyarma yetene\u011fine sahiptir.<\/li>
  • S. boulardii ayn\u0131 zamanda, siklik AMP \u00fcretimini uyarmak i\u00e7in adenilat siklaz\u0131 aktive ederek ishale neden olan toksinler \u00fcreten bir mikrop olan V. cholerae’nin neden oldu\u011fu bir durum olan Kolera’n\u0131n etkilerini engellemede de etkilidir. Etki mekanizmas\u0131n\u0131n, adenilat siklaz\u0131n uyar\u0131lmas\u0131n\u0131 inhibe ederek epitel h\u00fccrelerinde kolera-toksin kaynakl\u0131 cAMP konsantrasyonunu azaltan 120 kDa olarak bilinen bir proteaz\u0131n salg\u0131lanmas\u0131n\u0131 i\u00e7erdi\u011fi bulunmu\u015ftur. <\/li>
  • S. boulardii, enflamatuar ba\u011f\u0131rsak hastal\u0131\u011f\u0131 (IBD) olan hastalar i\u00e7in etkili bir tedavidir. \u0130BH, kar\u0131n a\u011fr\u0131s\u0131, kal\u0131n ba\u011f\u0131rsak iltihab\u0131, ba\u011f\u0131rsak ge\u00e7i\u015finin bozulmas\u0131, kab\u0131zl\u0131k veya ishal, dispepsi ve \u015fi\u015fkinlik gibi yayg\u0131n semptomlarla karakterizedir. Bu semptomlar\u0131n \u00e7o\u011fu mikroflora dengesizli\u011finin bir sonucudur. S. boulardii tedavisinin IBD’nin t\u00fcm semptomlar\u0131n\u0131 azaltt\u0131\u011f\u0131 bulunmu\u015ftur. <\/li>
  • S. boulardii, E. histolylica taraf\u0131ndan geli\u015ftirilen lezyonlar\u0131n miktar\u0131n\u0131 ve \u015fiddetini azalt\u0131r.<\/li>
  • S. boulardii’nin, halihaz\u0131rda remisyona girmi\u015f Crohn Hastal\u0131\u011f\u0131 olan hastalar\u0131n n\u00fcksetmesini \u00f6nlemede etkili bir ara\u00e7 oldu\u011fu bulunmu\u015ftur. Ayr\u0131ca, S. boulardii’nin \u00dclseratif Kolit ile ili\u015fkili gastrointestinal semptomlar\u0131 ve ishali azaltmada avantajl\u0131 oldu\u011fu bulunmu\u015ftur. <\/li>
  • S. boulardii’nin, ince ba\u011f\u0131rsa\u011f\u0131n i\u00e7ini kaplayarak besin emilimini engelleyen Giardia lamblia bakterisinin neden oldu\u011fu bir durum olan giardiasis ile de m\u00fccadele etti\u011fi g\u00f6sterilmi\u015ftir.<\/li>
  • S. boulardii, \u00f6zellikle akut enfeksiy\u00f6z ishale neden olan E.coli ve S. typhi olarak bilinen patojenik bakterilere kar\u015f\u0131 m\u00fckemmel anti-mikrobiyal etkiler sergiler. Mannoza duyarl\u0131 yap\u0131\u015fma olarak bilinen etki \u015fekli, patojenik bakterilerin lektin resept\u00f6rleri arac\u0131l\u0131\u011f\u0131yla S. boulardii y\u00fczeyindeki belirli b\u00f6lgelere ba\u011flanmas\u0131n\u0131 i\u00e7erir. Bu geri d\u00f6n\u00fc\u015f\u00fc olmayan yap\u0131\u015fma sayesinde patojen bakterilerin f\u0131r\u00e7a s\u0131n\u0131r\u0131n\u0131 istila etmesi engellenir ve rahat\u00e7a at\u0131l\u0131r. <\/li>
  • Yukar\u0131dakiler gibi bakteriyel enteropatojenler, t\u00fcm Gezgin \u0130shali (TD) vakalar\u0131n\u0131n yakla\u015f\u0131k %80’inden sorumludur. S. boulardii’nin ishal i\u00e7in etkili bir ila\u00e7 oldu\u011fu kan\u0131tlanmakla kalmam\u0131\u015f, \u00e7al\u0131\u015fmalar \u00f6nleyici bir tedbir olarak (yola \u00e7\u0131kmadan 5-7 g\u00fcn \u00f6nce al\u0131nan) S. boulardii t\u00fcketiminin ishal riskini azaltt\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. <\/li>
  • S. boulardii’nin viral enfeksiyonlarla ili\u015fkili ishali etkili bir \u015fekilde tedavi etti\u011fi bulunmu\u015ftur. En \u00e7ok \u00e7al\u0131\u015f\u0131lanlar aras\u0131nda HIV vir\u00fcs\u00fc (AIDS) ile ili\u015fkili kronik ishal yer almaktad\u0131r. S. boulardii, plasebo alan bir kontrol grubu olu\u015fturularak Evre IV AIDS hastalar\u0131na verilmi\u015ftir. Sadece 18 ay sonra, v\u00fccut a\u011f\u0131rl\u0131\u011f\u0131nda art\u0131\u015f (plasebo verilen hastalar\u0131n durumu \u00f6nemli \u00f6l\u00e7\u00fcde k\u00f6t\u00fcle\u015fmeye devam ederken) ve gastrointestinal semptomlarda azalma dahil olmak \u00fczere dramatik iyile\u015fmeler g\u00f6r\u00fcld\u00fc. <\/li><\/ul>

    Saccharomyces boulardii’de mevcut \u00e7e\u015fitler:<\/h2>
    • Toz<\/li><\/ul>

      SACCHAROMYCES BOULARDII NAtural ve organik<\/h2>

      F\u0131r\u0131nc\u0131 mayas\u0131ndan elde edilen SACCHAROMYCES BOULARDII \u00fcr\u00fcn\u00fcm\u00fcz vejetaryen diyetler i\u00e7in uygundur ve ORGAN\u0130K EKO SERT\u0130F\u0130KA ile sa\u011flanabilir.<\/p>

      Sertifikalar:<\/strong><\/h2>
      • +GMP<\/li>
      • BRC<\/li>
      • GDO’suz<\/li>
      • Alerjen i\u00e7ermez<\/li>
      • Ko\u015fer\/Helal sertifikal\u0131<\/li><\/ul>

        SACCHAROMYCES BOULARDII uygulamalar\u0131<\/h2>
        • Beslenme ve Diyet \u00dcr\u00fcnleri<\/li>
        • Kuru kar\u0131\u015f\u0131m \u00fcr\u00fcnler<\/li>
        • Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00fc\u00e7lendiren g\u0131dalar<\/li>
        • Kilo verdiren yiyecekler<\/li>
        • Ya\u015flanma kar\u015f\u0131t\u0131 g\u0131dalar<\/li>
        • Hayvan beslenmesi<\/li><\/ul>

          Van Wankum Malzemeler<\/h2>

          Van Wankum Ingredients, \u00fcr\u00fcnleri ve ilkeleri i\u00e7in her zaman \u00e7evre dostu ve “ye\u015fil” f\u0131rsatlar aramaktad\u0131r.\nM\u00fc\u015fterilerimizle uzun vadeli ili\u015fkiler ve y\u00fcksek kaliteli hizmet i\u00e7in var\u0131z. L\u00fctfen bir Selenyum Mayas\u0131 numunesi talep etmekten veya sorular\u0131n\u0131z veya talepleriniz i\u00e7in do\u011frudan bizimle ileti\u015fime ge\u00e7mekten \u00e7ekinmeyin.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":0,"parent":0,"template":"","class_list":["post-11878","manufacturer","type-manufacturer","status-publish","hentry"],"acf":[],"yoast_head":"\nS. Boulardii \u00dcreticisi - Van Wankum Ingredients<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vw-ingredients.com\/tr\/m\/s-boulardii-ureticisi\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"S. Boulardii \u00dcreticisi - Van Wankum Ingredients\" \/>\n<meta property=\"og:description\" content=\"Saccharomyces boulardii nedir? Saccharomyces boulardii, ilk olarak 1934 y\u0131l\u0131nda Henri Boulard ad\u0131nda bir Frans\u0131z bilim adam\u0131 taraf\u0131ndan \u00c7inhindi’ndeki li\u00e7i ve mangosten meyvelerinden izole edilen tropikal bir maya t\u00fcr\u00fcd\u00fcr. 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Boulardii \u00dcreticisi - Van Wankum Ingredients","og_description":"Saccharomyces boulardii nedir? Saccharomyces boulardii, ilk olarak 1934 y\u0131l\u0131nda Henri Boulard ad\u0131nda bir Frans\u0131z bilim adam\u0131 taraf\u0131ndan \u00c7inhindi’ndeki li\u00e7i ve mangosten meyvelerinden izole edilen tropikal bir maya t\u00fcr\u00fcd\u00fcr. 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