Product Name: Mesalazine
IUPAC Name: 5-Amino-2-hydroxybenzoic acid
Chemical formula: C7H6NO3
Similar Names: Many names worldwide, including Mesalamine, Azacol, Lialda, Pentasa, and Apriso
CAS No.: [89-57-6]
ATC code: A07EC02
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn’s disease. It is sold in an oral form to maintain remission in Crohn’s disease, and as a rectal suppository and an enema for the lower bowel conditions. It is generic and sold under many brand names worldwide, and there are many formulations.
Mesalazine is the active moiety of sulfasalazine, which is metabolized to sulfapyridine and mesalazine. It is also the active component of the prodrug balsalazide along with the inert carrier molecule 4-aminobenzoyl-beta-alanine.
Benefits of Mesalazine:
- Used in the Treatment of inflammatory bowel disease
- Mesalazine works in the intestines. It inhibits inflammation in the intestinal wall.
- Used in the Treatment of chronic intestinal ulcerative colitis.
- Used in the Treatment of Crohn’s disease.
Mesalazine is available in different grades:
Certifications and Standards:
- European pharmacopoeia